Anime you should think about watching:
The first two here are new anime just airing now. Gosick has two episodes out and Hourou Musuko has one right now.
Gosick - This is an interesting one. It takes place in a Victorian setting in some made up country in europe. The main character is a Japanese exchange student and has been nicknames the Black Reaper because of his black hair and dark eyes. One day he meets a girl in the botanical garden above the library who looks like a doll (ZOMG GOTH/VICTORIANLOLI!&!!). The show is based around the fact that she is insanely smart and generally solves mysteries very quickly and easily. Overall the show has great animation, and it's a nice take on a genre I'm usually a bit skeptical of (I generally dont like "mystery" shows that play up that things are so amazingly mysterious). The characters seem to have fairly well fleshed out ideals and histories. Definitely one I'd suggest following.
Hourou Musuko AKA Wandering Son - This show is not for everyone. Shuicihi Nitori is the main character, at first glance a shy and quiet boy, but there's a deeper reason for that. Shuichi is not happy being a boy, and he has a habit of wearing girls' clothes. He is also friends with his classmate Yoshino Takatsuki, a tomboyish girl who wants to wear a boy's uniform. This show examines the issues of gender identity in a very frank fashion; it doesn't play things up, there's no slapstick, or jokes at the show's expense. It's a serious take on trans-gendered children in middle school, and the problems they face. The animation is beautiful, and looks like it was entirely animated with watercolors. I've only see on episode, but I am definitely going to finish this one.
These are anime that have second seasons coming out now, which I haven't started yet because I just began watching the first one:
Mitsudomoe - How bad can elementary school children be? These 3 sisters will show you. This show is vulgar, violent, and sometimes downright deranged. It's Satoshi Yabe's first day teaching, and he's assigned class 6-3, home of the Marui Triplets, Futaba, Mitsuba, and Hitoha. They waste no time in torturing and harassing him, doing everything from smacking him in the face with a porn magazine, trying to hit him in the balls (under the pretense that if he is injured there the nurse, which he likes, would have to examine him there and that would somehow kick start their relationship).t's full of in jokes later on as well, seeing as the first episode of the second season is an episode of the show-within-a-show which makes fun of Zentai shows. It's twisted, hilarious, and sometimes just downright insane, and I definitely recommend it.
I'll add more later.